Cryptosporidiosis in paediatric renal transplantation

Abstract  Diarrhoea in transplantation may be secondary to infectious agents and immunosuppressive drugs. The use of combined immunosuppressive drugs increases the incidence of infectious diarrhoea. We retrospectively collected all diarrhoea episodes during a 3-year period in 199 pediatric renal transplant recipients, including 47 patients receiving a kidney transplant during this period. We diagnosed 64 diarrhoea episodes (32% of the patients, 10.7% per year). Fourteen diarrhoea episodes could be attributed to the immunosuppressive treatment, and 12 remained without diagnosis. Nineteen patients (<10%) receiving mycophenolic acid (MPA) developed diarrhoea, 14 of whom had episodes attributable to the immunosuppressive treatment. Reducing the MPA dose or switching to anoth...

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Expression of matrix metalloproteinases and their inhibitors in cords and nodules of patients with Dupuytren�"s disease

Conclusions  The balance between MMPs and their natural inhibitors is disturbed in patients with Dupuytren�"s disease. The decrease in MMP-to-TIMP expression can cause increased synthesis and deposition of collagen, leading to palmar fibromatosis. The high expression of MMP2 may represent an unsuccessful attempt to reduce collagen deposition. In the future, a treatment that downregulates TIMPs but increases the activity of MMPs may be an appropriate therapy for Dupuytren�"s disease. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0726-3AuthorsDietmar Ulrich, Aachen University of Technology Department of Plastic Surgery, Hand Surgery, Burn Unit, University Hospital, Medical Faculty of the University of Technology Pauwelsstrasse 30 5207...
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Needle Aponeurotomy for Dupuytren's Contracture

Purpose: To review the effectiveness and safety of needle aponeurotomy for Dupuytren's contracture in a Chinese population. Methods: Seven males and one female, age range 50�80 underwent needle aponeurotomy for Dupuytren's contracture. Needle aponeurotomy was performed under local anesthesia using a 23-gauge hypodermic needle. The cord is placed on tension and the needle is inserted in the same local anesthetic injection sites. The needle is then rotated and the sharp bevel edge is used to make small perpendicular cuts in the fibers of the cord a few millimeters in depth. The needle is then rotated and swiped transversely. Other punctures were administered in the same manner along the cord until the desired extension was gained. After the procedure was complete, the finger was splinted ...

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Miley Cyrus' Boyfriend Liam: We're in Love!

Love was in the air last night at 'The Last Song' movie premiere in Hollywood and the huge smile on Miley Cyrus' face said it all--she's in love!Miley and her on and off screen boyfriend Liam Hemsworth made their red carpet debut while promoting their new romantic movie 'The Last Song' and while they did interviews separately, they weren't far from each others minds.Liam spoke to Hollyscoop.com about his new girl telling us that working with Miley was "Great! Really really great!"Miley's Boyfriend: I Had No Idea She Was FamousAnd the romance didn't stop after the director yelled "cut." They
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BOY GEORGE CELEBRATES TWO YEARS OFF DRUGS

BOY GEORGE celebrated a landmark achievement last week (end21Mar10) - he' s been drug-free for two years.The former Culture Club star has endured a lengthy battle with addictio n, but he finally beat his demons a year before he was jailed last Januar y (09) for the false imprisonment and assault of a male escort in 2007.Boy George, real name George O'Dowd, has previously credited his prison stint with improving his life "more than 100 per cent" as it forced him to kick his drug habit.And O'Dowd has remained "clean" since his release last May (09).Speaking to British TV host
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COLE ORDERED TO PAY DAMAGES TO EVENT PROMOTER

R&B singer KEYSHIA COLE has been ordered to pay almost $160,000 (=C2=A310 6,666) in damages to an event promoter over a concert no-show.The Last Night hitmaker was allegedly due to play a gig in 2006 and was handed $15,000 (=C2=A310,000) upfront to perform, but she failed to show up to the event, a New Jersey court heard on Thursday (25Mar10).The judge ruled against Cole after branding the singer's testimony "con fused and at times nonsensical", adding, "that it appears at times that s he was not literate".Cole has been ordered to pay the sum to the company, reports TMZ.com (K
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April Nevels "Krazy Praize" Set to Make Worldwide TV Debut March 26

ATLANTA, GA - March 24, 2010 - April Nevels will make her worldwide television debut as a solo artist Friday, March 26 on The Word Network with a performance of �Krazy Praize� the first single and title track from her forthcoming debut album. She is scheduled to be the featured musical guest of �Rejoice in the Word with Bishop Greg Davis� which airs at 8:30 p.m. Eastern and is broadcast in over 200 countries including an audience of 60 million households in the U.S. alone. Produced by Rob Sayles, world-class musician and drummer for platinum-selling soul singer Lyfe Jennings, �Krazy
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